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ESTOOLS - Platforms for biomedical discovery with human ES cells
Scientific coordinator: Peter Walter Andrews ()
Period: 2006-07-26 - 2010-07-25
The pluripotent nature of human embryonic stem (hES) cells presents unprecedented opportunities for studying human cellular differentiation and pathogenesis. Furthermore, hES cells offer a new resource for cellular transplantation in human degenerative disease and a powerful platform for ...
EUROSPAN - EUROpean Special Populations Research Network: quantifying and harnessing genetic variation for gene discovery
Scientific coordinator: Harry Campbell ()
Period: 2006-03-01 - 2009-02-28
This project will study 5 special populations throughout Europe which represent a unique resource for genomic research. It will quantify genetic variation in genes known to be involved in health and disease and will harness this variation to identify novel variants. The project will build on the ...
EURATOOLS - European Rat Tools for Functional Genomics
Scientific coordinator: Timothy J. Aitman ()
Period: 2006-03-01 - 2010-02-28
Determining the molecular basis of natural phenotypic variation, including inter-individual susceptibility to common diseases, is a central challenge of post-genome genetics. The rat is a leading model species for research in physiology, pharmacology and toxicology, and for the study of a wide ...
POPULATION BIOBANKS - Harmonising population-based biobanks and cohort studies to strenghten the foundation of European biomedical science in the post-genome era
Scientific coordinator: Camilla Stoltenberg ()
Period: 2006-03-01 - 2009-02-28
This coordination action aims to establish a collaborative research network that will identify and explore key issues that will help to ensure that Europe makes best use of its rich array of population-based biobanks and longitudinal cohort studies. These include major cohorts that already exist ...
MED-RAT - New Tools to Generate Transgenic and Knock-out Mouse and Rat Models
Scientific coordinator: Andras Janos Dinnyes ()
Period: 2006-03-01 - 2009-02-28
Model organisms are essential to study the genetic basis of human diseases. Transgenic mammalian models, especially genetic knock-out mice catalysed the progress. To continue the advancement, further sophisticated and refined models are crucially needed to study the genetic basis and manifestations ...
BACRNAS - Non-coding RNAs in bacterial pathogenicity
Scientific coordinator: Renée Schroeder ()
Period: 2006-02-01 - 2009-01-31
From being regarded a minor class of RNAs, ncRNAs (noncoding RNAs, mostly antisense) have recently emerged as ubiquitous key players in important life processes in animals, plants, fungi and metazoans. Similarly, 65 small ncRNAs, encoded by the E. coli genome, have been recently identified, and ...
ENDOTRACK - Tracking the Endocytic Routes of Growth Factor Receptor Complexes and their Modulatory Role on Signalling
Scientific coordinator: Marino Zerial ()
Period: 2006-02-01 - 2010-01-31
Endocytic trafficking plays a more active role in the regulation of polypeptide growth factor (GF) signalling than recognized before. Despite great progress in the description of the endocytic routes and their molecular regulation, we are far from a complete understanding of the endocytic ...
PLURIGENES - Pluripotency associated genes to de-differentiate neural cells into pluripotent cells
Scientific coordinator: Jean-Stéphane Joly ()
Period: 2006-01-01 - 2008-12-31
A first step to regenerative medicine is to find a means to cause controlled de-differentiation of adult tissue. Plurigenes aims at achieving major breakthroughs in the discovery and understanding of the function of genes controlling pluripotency in the central nervous system. These later could ...
RUBICON - Role of Ubiquitin and Ubiquitin-like Modifiers in Cellular Regulation
Scientific coordinator: Masucci Maria ()
Period: 2006-01-01 - 2010-12-31
Our objective is to create the conditions for the rapid progress of research on the molecular principles of post-translational modifications of proteins by linkage of ubiquitin and ubiquitin-like molecules, the regulatory role of such modifications in basic biological processes and their ...
EUCLOCK - Entrainment of the Circadian Clock
Scientific coordinator: Till Roenneberg ()
Period: 2006-01-01 - 2010-12-31
The circadian clock is a basic biological process that enables organisms to anticipate daily environmental changes by adjusting behaviour, physiology and gene regulation. It impacts health and quality of life in regulating sleep and well-being, in the consequences of shift-work, in medical ...
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Last updated on 2014-04-08 at 10:55